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  • Innoprot
    • Productos
      • Human Primary Cells
        • Gastrointestinal Cell System

Human Intestinal Microvascular Endothelial Cells

Reference: P10753

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Data Sheet

Human Intestinal Microvascular Endothelial Cells (HIMEC) provided by Innoprot are isolated by ScienCell Research Laboratories from human Intestinal Tissue. HIMEC are cryopreserved at passage one and delivered frozen.

Innoprot also offers optimized medium and reagents for the growth of Human Intestinal Microvascular Endothelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HIMEC culture.


Endothelial cells lining the microvasculature are known to play a critical “gatekeeper” role in the inflammatory process through their ability to recruit circulating immune cells into tissues and foci of inflammation. Studies show that IMEC exhibit a strong immune response to LPS challenge and play a critical regulatory role in gut inflammation. Pharmacological inhibition of NOS in activated HIMEC resulted in a significant increase in leukocytes binding. Gene expression profile study reveals that IMEC express biotinidase, which is involved in biotin recycling. In vitro culture of HIMEC enabled scientists to perform systematic analyses of the cytokine profiles with regard to mRNA expression and protein secretion, &to compare such data with cytokine profiles concomitantly displayed by other endothelial cells.

Number of Cells

  • 5x105 cells / vial

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