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Innoprot

  • Innoprot
    • Productos
      • Human Primary Cells
        • Skeletal Cell System

Human Osteoblasts

Reference: P10971


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Data Sheet

Human Osteoblasts (HO) provided by Innoprot are isolated from adult human femur or from human calvariae. Based on their origin you can select between Human Calvarial Osteoblasts and Human Femoral Osteoblasts. After isolation, Human Osteblasts are cryopreserved at primary cultures and delivered frozen.

Innoprot also offers optimized medium and reagents for the growth of Human Osteoblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HO culture.


Human Osteoblasts Features


Bone is a dynamic tissue, being continuously remodeled by the coordinated actions of osteoclasts and osteoblast lineage. Osteoblasts, the bone-forming cells, are derived originally from pluripotent mesenchymal stem cells. They synthesize and secrete organic extracellular matrix, osteoid, which is composed primarily of type I collagen. Osteoid is calcified by osteoblasts and during this process the cells become encased in lacunae within the calcified material and become osteocytes. Osteoblasts express protease-activated receptor-1 and vescular endothelial cell growth factor . Studies show that Leukemia inhibitory factor can bind to the osteoblast cell surface and induce bone formation both in vitro and in vivo.


Human Osteoblasts - References

  • P10971: Human Calvarial Osteoblasts: 500.000 cells/vial
  • P10979: Human Femoral Osteoblasts: 500.000 cells/vial

  

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