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  • Innoprot
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      • Human Primary Cells
        • Dermal Cell System

Human Hair Follicle Inner Root Sheath Cells

Reference: P10884

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Data Sheet

Human Hair Follicle Inner Root Sheath Cells (HHFIRSC) provided by Innoprot are isolated by ScienCell Research Labs from human hair follicle inner root sheath. HHFIRSC are cryopreserved at primary culture and delivered frozen. HHFIRSC are guaranteed to further expand for 15 population doublings in the condition provided by ScienCell Research Laboratories.

Innoprot also offers optimized medium and reagents for the growth of Human Hair Follicle Inner Root Sheath Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HHFIRSC culture.


The inner root sheath (IRS) of human hair follicles consists of three concentric cell layers: the cuticle, Huxley's layer, and Henle's layer. All three layers are formed from the peripheral mass of matrix cells in the hair bulb. The formation of the IRS during the evolution of mammalian epidermis allowed the physiological exit of hairs produced inside the skin. Immunohistochemical staining indicates the human IRS cells express K6irs1, K6irs2, K6irs3, and K6irs4, the inner-root-sheath-specific type II epithelial keratins. In situ hybridization study found FGF-22 mRNA in the skin was preferentially expressed in the inner root sheath of the hair follicle. Therefore, FGF-22 is expected to be a unique FGF that plays a role in hair development.

Number of Cells

  • 5x105 cells / vial

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