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Innoprot

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      • Human Primary Cells
        • Hepatic Cell System

Human Intrahepatic Biliary Epithelial Cells

Reference: P10654


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Data Sheet

Human Intrahepatic Biliary Epithelial Cells (HIBEpiC) provided by Innoprot are isolated from human liver tissue. HIBEpiC are cryopreserved after purification and delivered frozen. HIBEpiC are guaranteed to further expand for 10 population doublings in the condition provided in this technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Intrahepatic Biliary Epithelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HIBEpiC culture.
 

Features/Benefits


IBEpiC line the intrahepatic biliary tree, a complex network of tubular conduits of different diameters within the liver. They comprise only 3 – 5% of the total population of liver cells, yet produce as much as 40% of the daily output of bile. A number of studies have demonstrated that IBEpiC play important roles in maintaining, modifying and augmenting the composition of canalicular bile by a coordinated series of hormone-regulated secretary and absorptive processes. IBEpiC also appear to have active immunologic roles in both innate and adaptive immune responses; IBECs secrete chemokines and cytokines and serve to localize the immune response by expressing critical cell adhesion molecule. Under basal conditions, IBEpiC are thought to be mitotically dormant. However, IBEpiC proliferate markedly in response to a number of perturbations.  Cultured Human IBEpiC (HIBEpiC) are a useful in vitro model for studying biliary cirrhosis and liver disease.
 

Number of Cells

  • 5x105 cells / vial

  

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