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Innoprot

  • Innoprot
    • Productos
      • Human Primary Cells
        • Hepatic Cell System

Human Hepatic Sinusoidal Endothelial Cells

Reference: P10652


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Data Sheet

Human Hepatic Sinusoidal Endothelial Cells (HHSEC) provided by Innoprot are isolated from human normal liver. HHSEC are cryopreserved immediately after purification and delivered frozen. HHSEC are guaranteed to further expand for 15 population doublings in the conditions described in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Hepatic Sinusoidal Endothelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HSEC culture.


Hepatic Sinusoidal endothelial Cells Features


SEC are liver microvascular endothelial cells with a unique phenotype reminiscent of dendritic cells and a unique function as antigen-presenting cells for CD4+ T cells. Thus, SEC represent a new type of organ-resident "non-professional" antigen-presenting cell that appears to be involved in the local control of the immune response and the induction of immune tolerance in the liver. SEC express well-characterized surface receptors and differ morphologically and metabolically from large-vessel endothelia. It has reported that SEC are dynamic regulators of porosity that respond rapidly and locally to environmental zonal stimuli during liver regeneration. Due to its strategic position in the liver sinusoid, SEC dysfunction and structural alterations have far-reaching repercussions for the whole liver.


Human Hepatic Sinusoidal Endothelial Cells - Product Size

  • Cryopreserved: 5x105 cells / vial
  • Proliferating: T-25 Flask

   

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