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Innoprot

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      • Human Primary Cells
        • Urethral Cell System

Human Bladder Stromal Fibroblasts

Reference: P10988


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Data Sheet

Human Bladder Stromal Fibroblasts (HBdSF) are isolated from the human bladder by Sciencell Research Laboratories. HBdSF are cryopreserved after purification and delivered frozen. HBdSF are characterized by immunofluorescence with antibodies specific to vWF VIII and CD31 (PECAM-1) and by uptake of DiI-Ac-LDL. HBdSF are guaranteed to further expand for 15 population doublings under the conditions provided by in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Fibroblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HBdSF culture.


Features/Benefits


Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of the easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. There is good evidence that fibroblasts in different parts of the body are intrinsically different. Fibroblasts within tissues are exposed to a dynamic mechanical environment, which influences the structure integrity of both healthy and healing soft tissue. Fibroblasts secrete a nonrigid extracellular matrix that is rich in type I and/or type III collagen. As cells of mesenchymal origin, human bladder stromal fibroblasts (HBdSF) also secrete FGF-7, which interact primarily with bladder epithelial cells. FGF-7 secreted by HBdSF is essential for stimulating the formation of a multilayered stratified bladder epithelium.

Number of Cells

  • 5x105 cells / vial

 

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