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Innoprot

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      • Human Primary Cells
        • Urethral Cell System

Human Bladder Microvascular Endothelial Cells

Reference: P10989


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Data Sheet

Human Bladder Microvascular Endothelial Cells (HBdMEC) are isolated from the human bladder. HBdMEC are cryopreserved after purification and delivered frozen. HBdMEC are characterized by immunofluorescence with antibodies specific to vWF VIII and CD31 (PECAM-1) and by uptake of DiI-Ac-LDL. HBdMEC are guaranteed to further expand for 10 population doublings under the conditions provided by in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Endothelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HBdMEC culture.


Features/Benefits


The bladder is a hollow sphere, with the wall of the sphere comprising the serosa, muscularis, submucosa, musculris mucosa, and lamina propria. Embedded within these structures is a circulatory system, sensory and motor neurons, and an immune system. The endothelial cells lining the microvasculature of the circulatory system are known to play a critical “gatekeeper” role in the inflammatory process through their ability to recruit circulating immune cells into tissues and foci of inflammation. Stimulation of endothelial cells in the bladder wall by thrombin or tryptase may result in a similar patter of phospholipid metabolite production and may play a role in the inflammatory process in IC. To be able to study the role of endothelial cell in physiological and inflammatory condition, the HBdMEC culture provides a useful in vitro model.

Number of Cells

  • 5x105 cells / vial

  

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