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Innoprot

  • Innoprot
    • Productos
      • Human Primary Cells
        • Ocular Cell System

Human Keratocytes

Reference: P10872


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Data Sheet

Human Keratocytes (HK) provided by Innoprot are isolated by ScienCell Research Laboratories from human cornea. HK are cryopreserved at primary culture and delivered frozen.  HK are guaranteed to further expand for 15 population doublings at the condition provided by ScienCell Research Laboratories.

Innoprot also offers optimized medium and reagents for the growth of Human Keratocytes which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HK culture.

Features/Benefits


The keratocyte, or corneal fibroblast, is a highly specialized cell that is sandwiched between orthogonally arranged layers of collagen lamellae in the corneal stroma. Under normal conditions, the keratocyte in the adult cornea is a relatively quiescent cell. However, in the event of a corneal injury or trauma, the keratocytes differentiate into active, synthesizing cells and rapidly replace damaged stromal matrix. Cultured human keratocytes express functional IL-4Rs and IL-17R on cell surface, suggesting that these cells may contribute to the role of IL-4 and IL-17 as mediators of allergic reactions in the cornea. Changes in gene expression were reproducibly observed on keratocytes after interleukin-1 treatment which provides important insight in gene expression and suggests novel therapeutic targets for the control of corneal inflammation.

Number of Cells

  • 5x105 cells / vial

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