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Innoprot

  • Innoprot
    • Productos
      • Human Primary Cells
        • Ocular Cell System

Human Iris Pigment Epithelial Cells

Reference: P10875


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Data Sheet

Human Iris Pigment Epithelial Cells (HIPEpiC) provided by Innoprot are isolated from human healthy iris. HIPEpiC are cryopreserved at passage one and delivered frozen. HIPEpiC are guaranteed to further expand for around 10 population doublings in the conditions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Iris Pigment Epithelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HIPEpiC.

Features/Benefits


The iris is a pigmented disk with a variable aperture which forms the pupil of the eye. It is covered by squamous epithelium on anterior surface and 2 layers of pigmented epithelium on posterior. In recent years, Iris Pigmental Cells (IPE) have been transplanted into the subretinal space of eye to treat Retinal Pigment Epithelial Cell (RPE) defects. The grafted IPE were seen to survive for months. There was a remodeling of cellular layers in the subretinal space over time where grafted IPE joined the native RPE. The cellular response that developed exhibited macrophages and were similar to that observed following RPE transplantation. In vitro study also show that IPE expressing CD86, directly suppresses T cell activation via binding to cytotoxic T lymphocyte-associated antigen.

Number of Cells

  • 5x105 cells / vial

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