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Innoprot

  • Innoprot
    • Productos
      • Human Primary Cells
        • Reproductive cell System

Human Myometrial Microvascular Endothelial Cells

Reference: P10993


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Data Sheet

Human Myometrial Microvascular Endothelial Cells (HMMEC) provided from Innoprot are isolated by ScienCell Research Laboratories from human uterus. HMMEC are cryopreserved immediately after purification and delivered frozen. HMMEC are guaranteed to further culture at the conditions specified in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Endothelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro endothelial cells culture.


Features/Benefits


Myometrial microvascular endothelial cells (MMEC) are located in the myometrium between the endometrium and the serosa of the uterus and exhibit typical cobblestone morphology. During pregnancy, angiogenesis occurs through MMEC proliferation in order to support the hypertrophy of the myometrial smooth muscle cell layer. Significant evidence also indicates that endothelial cell dysfunction in the myometrium may contribute to the development of preeclampsia. In addition, MMEC proliferation and angiogenesis may play a role in the formation of leiomyomata. Studies have shown that MMEC express the oxytocin receptor, which may promote vasodilation in the microvasculature of the myometrium. Human MMEC are a useful in vitro model to elucidate the mechanisms of angiogenesis and to develop treatments for female reproductive tract disorders.

Number of Cells

  • 5x105 cells / vial
 

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