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Innoprot

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        • Reproductive cell System

Human Testicular Endothelial Cells

Reference: P10794


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Data Sheet

Human Testicular Endothelial Cells (HTEC) are isolated from human testis by Sciencell Research Laboratories. HTEC are cryopreserved at passage one and delivered frozen. HTEC are characterized by immunofluorescence with antibodies specific to vWF/Factor VIII, and by uptake of DiI-Ac-LDL. HTEC are guaranteed to further expand for 10 population doublings under the conditions provided by in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Testicular Endothelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HTEC culture.

Features/Benefits


Testicular Endothelial Cells (TEC), located in the mesonephros, migrate in the developing embryo from the mesonephros to form the testis vasculature during the process of testis cord formation. The migrating endothelial cells are also essential because they initiate cord formation by creating partitions for the Sertoli and Germ cells. Recent studies have shown that disrupting testis vascular development blocks testis cord formation and thereby prevents proper structural development of the testis. In addition, studies suggest that testicular endothelial cells have similar properties to brain endothelial cells and contribute to the establishment of the blood-testis barrier (BTB). Cultured Human TEC (HTEC) are a useful in vitro model to understand vascular defects in testis dysgenesis and may provide new insight for treatment of male reproductive disorders.


Number of Cells

  • 5x105 cells / vial
 

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