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  • Innoprot
    • Productos
      • Human Primary Cells
        • Reproductive cell System

Human Villous Mesenchymal Fibroblasts

Reference: P10959

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Data Sheet

Human Villous Mesenchymal Fibroblasts (HVMF) provided by Innoprot are isolated by ScienCell Research Laboratories from human placental villi. HVMF are cryopreserved at primary culture and delivered frozen. HVMF are guaranteed to further expand for 15 population doublings at the conditions provided by ScienCell Research Laboratories.

Innoprot also offers optimized medium and reagents for the growth of Human Villous Mesenchymal Fibroblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HVMF.


Fibroblasts are mesenchymal cells which are derived from the embryonic mesoderm. Since tissue-specific mesenchymal cells are essential for normal organ development, the villous mesenchymal fibroblasts (VMF) have been used as a model system for studying the cellular mechanisms involved in regulating human placental growth. The VMF lie directly beneath the villous basement membrane; they synthesize HGF, CSF-1, granulocyte CSF and IL-6 and play an important role in the regulation of trophoblast growth and function. Studies have shown that paracrine interaction between placental villous mesenchymal fibroblast and the cytotrophoblast in anchoring sites is required in stimulating trophoblast infiltration.

Number of Cells

  • 5x105 cells / vial

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