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Innoprot

  • Innoprot
    • Productos
      • Animal Primary Cells
        • Hepatic Cell System

Mouse Hepatic Sinusoidal Endothelial Cells

Reference: P10622


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Data Sheet

Mouse Hepatic Sinusoidal Endothelial Cells (MHSEC) are isolated by Innoprot from Swiss mice. MHSEC are packaged immediately after purification and delivered frozen. MHSEC are not recommend for expanding or long term cultures since these cells do not proliferate in vitro.

Innoprot also offers optimized medium and reagents for the culture maintenance of Mouse Hepatic Sinusoidal Endothelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro MSEC culture.

Features/Benefits


SEC are microvascular endothelial cells with a unique phenotype reminiscent of dendritic cells and a unique function as antigen-presenting cells for CD4+ T cells. Thus, SEC represent a new type of organ-resident "non-professional" antigen-presenting cell that appears to be involved in the local control of the immune response and the induction of immune tolerance in the liver. SEC express well-characterized surface receptors and differ morphologically and metabolically from large-vessel endothelia. It has reported that SEC are dynamic regulators of porosity that respond rapidly and locally to environmental zonal stimuli during liver regeneration. Due to its strategic position in the liver sinusoid, SEC dysfunction and structural alterations have far-reaching repercussions for the whole liver.


Size

  • 1 x106 cells in cryopreserved vials
  • T-25 Flask - Fresh Isolated MSEC

 

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