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Innoprot

  • Innoprot
    • Productos
      • Animal Primary Cells
        • Skeletal Cell System

Rat Osteoblasts

Reference: P10931


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Data Sheet

Rat Calvarial Osteoblasts (RCO) provided by Innoprot are isolated from the calvaria bone of neonatal Sprague-Dawley rats. RCO are cryopreserved at primary cultures and delivered frozen. RCO are guaranteed to further expand for 10 population doublings in the conditions provided by Innoprot.

Innoprot also offers optimized medium and reagents for the growth of Rat Calvarial Osteoblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HCO culture.


Features/Benefits


Bone is a dynamic tissue, being continuously remodeled by the coordinated actions of osteoclasts and osteoblast lineage. Osteoblasts, the bone-forming cells, are derived originally from pluripotent mesenchymal stem cells. They synthesize and secrete organic extracellular matrix, osteoid, which is composed primarily of type I collagen. Osteoid is calcified by osteoblasts and during this process the cells become encased in lacunae within the calcified material and become osteocytes. Osteoblasts express protease-activated receptor-1 and vescular endothelial cell growth factor . Studies show that Leukemia inhibitory factor can bind to the osteoblast cell surface and induce bone formation both in vitro and in vivo.


Size

  • Cryopreserved vial - 5x105 cells
  • T-25 Flask
  • 96-Well Plate

 

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