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Innoprot

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HiTSeeker ADORA2A (Adenosine Receptor 2A)

Reference: P30191


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Data Sheet

Each vial of HiTSeeker ADORA2A contains HEK293 cells stably expressing human Adenosine Receptor 2A with no tag. We offer this cell line as a “stable cell line” but we are now also offering vials of division-arrested cells (DA cells) in order to perform a small number of assays. Each vial of these DA cells contains 2.5 million cells, an enough number of cells to perform a complete experiment in a 96 well-plate or 384 well-plate.

Innoprot's HiTSeeker ADORA2A Cell Line has been designed to assay compounds or analyze their capability to modulate human Adenosine Receptor 2A. When an agonist (like NECA) binds to the ADORA2A a G protein is activated, which in turn, triggers a cellular response mediated by second messengers (cAMP). This cell line has been validated measuring cAMP increase in the cytosol. The high reproducibility of this assay allows monitoring Adenosine Receptor 2A activation process in High Throughput Screening.


Materials Provided


  • P30191: 2 vials of 3 million stably transfected HEK293 Cells expressing ADORA2A
  • P30191-DA: 1 vial with 2.5 million Division Arrested HEK293 Cells expressing ADORA2A (READY TO USE)
 

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