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Innoprot

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HiTSeeker ADORA2B (Adenosine Receptor 2B)

Reference: P30192


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Data Sheet

Each vial of HiTSeeker ADORA2B contains HEK293 cells stably expressing human Adenosine Receptor 2B with no tag. We offer this cell line as a “stable cell line” but we are now also offering vials of division-arrested cells (DA cells) in order to perform a small number of assays. Each vial of these DA cells contains 2.5 million cells, an enough number of cells to perform a complete experiment in a 96 well-plate or 384 well-plate.

Innoprot''''s HiTSeeker ADORA2B Cell Line has been designed to assay compounds or analyze their capability to modulate human Adenosine Receptor 2B. When an agonist (like NECA) binds to the ADORA2B a G protein is activated, which in turn, triggers a cellular response mediated by second messengers (cAMP). This cell line has been validated measuring cAMP increase in the cytosol. The high reproducibility of this assay allows monitoring Adenosine Receptor 2B activation process in High Throughput Screening.


Materials Provided


  • P30192: 2 vials of 3 million stably transfected HEK293 Cells expressing ADORA2B
  • P30192-DA: 1 vial with 2.5 million Division Arrested HEK293 Cells expressing ADORA2B (READY TO USE)
 

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