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Innoprot

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        • GPCR CELL LINES

HiTSeeker DRD5 (Dopamine Receptor D5)

Reference: P30122


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Data Sheet

Each vial of HiTSeeker DRD5 contains HEK293 cells stably expressing human Dopamine receptor D5 (DRD5) with no tag. We offer this cell line as a “stable cell line” but we are now also offering vials of division-arrested cells (DA cells) in order to perform a small number of assays. Each vial of these DA cells contains 2.5 million cells, an enough number of cells to perform a complete experiment in a 96 well-plate or 384 well-plate.

Innoprot's HiTSeeker DRD5 Cell Line has been designed to assay compounds or analyze their capability to modulate human Dopamine Receptor D5 (DRD5). When an agonist (like dopamine) binds to the DRD5 a G protein is activated, which in turn, triggers a cellular response mediated by second messengers (cAMP). This cell line has been validated measuring cAMP increase in the cytosol. The high reproducibility of this assay allows monitoring Dopamine Receptor D5 activation process in High Throughput Screening.


Materials Provided


  • P30122: 2 vials of 3 million stably transfected HEK293 Cells expressing DRD5
  • P30122-DA: 1 vial with 2.5 million Division Arrested HEK293 Cells expressing DRD5 (READY TO USE)
 

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