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Innoprot

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HiTSeeker PTGER1 (Prostaglandin E Receptor 1 - subtype EP1)

Reference: P30402


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Data Sheet

Each vial of HiTSeeker PTGER1 contains U2OS cells stably expressing human Prostaglandin E Receptor 1 (subtype EP1) with no tag. We offer this cell line as a “stable cell line” but we are now also offering vials of division-arrested cells (DA cells) in order to perform a small number of assays. Each vial of these DA cells contains 2.5 million cells, an enough number of cells to perform a complete experiment in a 96 well-plate or 384 well-plate.

Innoprot HiTSeeker PTGER1 Cell Line has been designed to assay compounds or analyze their capability to modulate human Prostaglandin E Receptor 1 - subtype EP1. When an agonist (like Prostaglandin E1) binds to the PTGER1 a G protein is activated, which in turn, triggers a cellular response mediated by second messengers (Ca). This cell line has been validated measuring Calcium increase in the cytosol. The high reproducibility of this assay allows monitoring Prostaglandin E Receptor 1 - subtype EP1 activation process in High Throughput Screening.


Materials Provided


  • P30402: 2 vials of 3 million stably transfected U2OS Cells expressing PTGER1
  • P30402-DA: 1 vial with 2.5 million Division Arrested U2OS Cells expressing PTGER1 (READY TO USE)
 

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