X

This site uses third parties to own and optimize your navigation and perform analytical work cookies. If you continue browsing, consider that you accept its use.
You can learn more at our Cookie Policy.

Innoprot

  • Innoprot
    • Productos
      • Human Primary Cells
        • Renal Cell System

Human Kidney Fibroblasts

Reference: P10666


Get your Price

Data Sheet

Human Renal Interstitial Fibroblasts are isolated from the human healthy renal tissue. HRIF are cryopreserved after passage one culture and delivered frozen. HHRIF are guaranteed to further expand for 15 population doublings under the conditions provided by in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Fibroblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HRIF culture.


Features/Benefits


As an excretory organ in the urinary system, the kidney greatly influences an individual’s well being by preserving homeostasis through regulating electrolytes, pH, and blood pressure among other control mechanisms. Comprising the majority of interstitial cells in the kidney, renal fibroblasts are responsible for the synthesis of collagen I of the extracellular matrix. Also, renal cortical fibroblasts synthesize erythropoietin, an important glycoprotein hormone that controls the production of red blood cells and renal medullary fibroblasts produce prostaglandins, a class of autocrine or paracrine hormones, which help maintain water and electrolyte homeostasis. Renal interstitial fibrosis, a disorder that may escalate to chronic kidney disease, is often correlated with excessive deposition of extracellular matrix by renal fibroblasts, the regulation of which process is under intensive research.

Number of Cells

  • 5x105 cells / vial
 

Related Products/Services



© Innoprot 2008 - Cell Based Assays for Drug Discovery Screening - Cookie Policy