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Innoprot

  • Innoprot
    • Productos
      • Human Primary Cells
        • Pulmonary Cell System

Human Pulmonary Alveolar Epithelial Cells

Reference: P10556


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Data Sheet

Human Pulmonary Alveolar Epithelial Cells (HPAEpiC) provided by Innoprot are isolated by ScienCell Research Laboratories from human lung tissue. HPAEpiC are cryopreserved at primary culture and delivered frozen.

Innoprot also offers optimized medium and reagents for the growth of Human Pulmonary Alveolar Epithelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HPAEpiC culture.

Features/Benefits

 

PAEpiC comprised of alveolar type I and type II epithelial cells, line more than 99% of the internal surface area of the lung. Type I cells are large squamous cells whose thin cytoplasmic extensions cover >95% of the internal surface area. They contain aquaporins and exhibit the highest osmotic water permeability of any mammalian cell type. Type II cells, which cover 2-5% of the surface area, produce, secrete, and recycle pulmonary surfactant. Type II cells contain Na+-, K+-ATPase and amiloride-sensitive epithelial Na+ channels. The currently accepted hypothesis is that Type II cells maintain pulmonary fluid homeostasis by regulating active Na+ transport in the lungs, whereas Type I cells are "inert" cells that provide solely a barrier function, rather than having active functions.

Number of Cells

  • 1x106 cells / vial

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