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        • Peripheral Blood Cell System

Human Peripheral Blood CD8+ Cytotoxic T Cells

Reference: P10586


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Data Sheet

CD8+ Cytotoxic T Cells are isolated from mononuclear cells by positive selection using immunomagnetic cell separation procedures.


Features/Benefits


CD8+ Cytotoxic T Cells fulfill the role of regulating and/or carrying out the body’s immune response by eliminating intracellular pathogens such as viruses, and some bacteria and parasites. Upon recognition of an infected cell, the CD8+ T cell initiates apoptosis through the targeted release of effector proteins contained in granules within the T cell.

Most CD8+ Cytotoxic T cells express T‐cell receptors (TCRs) that can recognize a specific antigenic peptide bound to Class I MHC molecules (present on all nucleated cells) and a glycoprotein called CD8. The MHC molecule keeps the Cytotoxic T cell and the target cell bound closely together during antigen‐specific activation.


Number of Cells

  • 5 x 106 cells/vial
  • 10 x 106 cells/vial
  • 25 x 106 cells/vial
 

Related Products/Services

  • P10588: Peripheral Blood Mononuclear Cells
  • P10585: Peripheral Blood CD4+ Helper T Cells
  • P10584: Peripheral Blood CD3+ Pan T Cells
 

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