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        • Peripheral Blood Cell System

Human Peripheral Blood M1 Macrophages

Reference: P10591-M1


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Data Sheet

M1 macrophages encourage inflammation. M1 macrophages are derived from purified CD14+ monocytes. CD14+ monocytes were positively selected via immunomagnetic beads and were cultured in the presence of GM‐CSF for 10 days. The M1 phenotyping was confirmed by morphology and the expression of specific biomarkers.


Features/Benefits


Macrophages are a type of white blood cell found in all tissues patrolling for potential pathogens. Macrophages are key players in the immune response, basically ridding the body of worn‐out cells, foreign substances, microbes, and cancer cells and alerting the immune system to the presence of invaders. Because macrophages possess the ability to eliminate pathogens and recruit and instruct other immune cells, they play a central role in protecting the body and contribute to the pathogenesis of inflammatory and degenerative diseases.


Number of Cells

  • 2 x 106 cells/vial
  • 5 x 106 cells/vial
  • 10 x 106 cells/vial
 

Related Products/Services

  • P10390: Human Dendritic Cells (Monocyte-Derived)
  • P10591: Human Macrophages-Mixed
  • P10591-M2: Human M2 Macrophages
 

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