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  • Innoprot
    • Productos
      • Stable Cell Lines
        • Immortalized Human Primary Cells

Immortalized Human Cardiac Fibroblasts

Reference: P10453-IM

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Data Sheet

HCF‐IM from Innoprot have been obtained immortalizing Human Cardiac Fibroblasts with Lenti‐SV40 Lentivirus. Immortalized cells were controlled passaging side by side with the primary cells. Primary cells go into senescence after the 3rd passage while the SV40‐tranduced cells go beyond 30 passages.

Innoprot also offers optimized medium and reagents for the growth of Immortalized Cardiac Fibroblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro culture.


The cardiac fibroblasts (CF) are the principal cell type of the heart. They provide structural support for cardiac myocytes and are responsible for extracellular matrix synthesis in the heart during growth and pathophysiological conditions. CF are an important cellular component of myocardial responses to injury and the source of paracrine growth factors. Their proliferation and synthesis of matrix is essential for scar formation at sites of myocardial infarction, cardiac fibrosis, and is often complicated by cardiac hypertrophy. CF culture has been widely used as a model to study the cardiac matrix remodeled by physiological (exercise) and pathological (hypertension) stressors.


  • Ref: P10453-IM: Immortalized Human Cardiac Fibroblasts

Number of Cells

  • 1x106 cells / vial


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