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Innoprot

  • Innoprot
    • Productos
      • Stable Cell Lines
        • Immortalized Human Primary Cells

Immortalized Human Conjunctival Epithelial Cell Line

Reference: P10870-IM


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Data Sheet

HConEpiC‐IM from Innoprot have been obtained immortalizing Human PrimaryConjunctival Epithelial Cells with Lenti‐SV40 Lentivirus. Immortalized cells were controlled passaging side by side with the primary cells. Primary cells go into senescence after the 3rd passage while the SV40‐tranduced cells go beyond 30 passages.

Innoprot also offers optimized medium and reagents for the growth of Immortalized HConEpiC which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro culture.


Features/Benefits


The conjunctival epithelium is a stratified, non-keratinized epithelium. It can be distinguished by the corneal epithelium by the expression of different cytokeratins, mucins and by the presence of glycocalix. Decrease or loss of mucin/glycocalix production generates squamous metaplasia, which may lead to dry eye and ocular surface diseases. Human conjunctival epithelial cells represent potential target cells for mast cell mediators. They respond to histamine by generating inositol phosphates, mobilizing intracellular calcium, and then secreting proinflammatory cytokines like interleukin-6 and interleukin-8.


Number of Cells

  • 1x106 cells / vial
 

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