Green Fluorescent RKO Cell Line

Reference: P20135

950,00

Green Fluorescent RKO Cell Line (aka LINTERNA RKO) has been developed through stable transfection of RKO cell line with tGFP. This cell line expresses green fluorescent protein gene sequences as free cytoplasmatic proteins. Each vial of cells contains more than 3 million viable cells stably expressing tGFP with G418 resistance gene.

LINTERNA RKO Cell line is ready to use in cell-based assay applications. This stably transfected clonal cell line provides consistent levels of expression, which helps simplify the interpretation of results. Green Fluorescent RKO Cell Line also allow to stablish in vitro models for HIgh Throughput and High Content Screening.

Green Fluorescent RKO Cell Line are suitable for both, in vitro and in vivo experimentation. About RKO Cell line: RKO cells are a human colon cancer cell line useful in research on colorectal cancer. They originate from a moderately differentiated colon adenocarcinoma and are distinct due to their wild-type p53 status, which is rare among many cancer cell lines. This characteristic makes RKO cells especially useful for investigating p53 function and studying DNA repair mechanisms and apoptosis within colorectal cancer contexts. With an epithelial-like structure, RKO cells are known for their genetic stability and responsiveness to various genetic and pharmacological interventions. They play a crucial role in studies that examine cancer progression pathways, such as cell cycle control, signal transduction, and metastasis. RKO cells help researchers understand how certain genes and environmental factors influence colorectal cancer and serve as a model for evaluating the effectiveness of anti-cancer treatments. About turboGFP protein: tGFP is an improved variant of the green fluorescent protein CopGFP from copepoda Pontellina plumata (Arthropoda; Crustacea; Maxillopoda; Copepoda). It possesses bright green fluorescence (excitation/ emission max = 482/ 502 nm) that is visible earlier than fluorescence of other green fluorescent proteins. TurboGFP is useful for applications where fast appearance of bright fluorescence is crucial. It is also useful for cell and organelle labeling and tracking the promoter activity.
  • Reference: P20135
  • Size/Quantity: 3x10⁶ cells / vial
  • Resistance Gene: G418
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice

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