Mitochondria in the context of Parkinson’s disease

Parkinson’s disease (PD) is the second most common neurodegenerative disease, affecting 1–2% of the population over the age of 65. Rigidity, bradikynesia, postural instability and tremor are the principal clinical characteristics of this disease, caused by the progressive loss and degeneration of dopaminergic neurons in the Substantia nigra pars compacta (SNpc). Tremor and motor impairment…