Arginine Vasopressin 1A receptor belongs to the same subfamily of G-protein coupled receptors of AVPR1B, V2R and OTR receptors. The activity of Arginine Vasopressin receptor 1A (AVPR1A) mediated by Gq/G11, stimulates a phosphatidylinositol-calcium second messenger system. V1A Vasopressin Receptor Assay from Innoprot allows the measurement of AVPR1A receptor activation by Calcium concentration increase in the cytosol.
Cell line used: HiTSeeker AVPR1A Cell Line
Readout: Calcium Flux
Agonist: Vasopressin
EC50 Agonist: 2.1 x 10-9 M for Calcium Flux
Type of Assay: Cell-based/Functional
Detection Method: Fluorimetry
Assay: Vasopressin Receptors