Arginine Vasopressin 1A receptor belongs to the same subfamily of G-protein coupled receptors of AVPR1B, V2R and OTR receptors. The activity of Arginine Vasopressin receptor 1A (AVPR1A) mediated by Gq/G11, stimulates a phosphatidylinositol-calcium second messenger system. V1A Vasopressin Receptor Assay from Innoprot allows the measurement of AVPR1A receptor activation by Calcium concentration increase in the cytosol.

Cell line used: HiTSeeker AVPR1A Cell Line

Readout: Calcium Flux

Agonist: Vasopressin

EC50 Agonist: 2.1 x 10-9 M for Calcium Flux

Type of Assay: Cell-based/Functional

Detection Method: Fluorimetry

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