5-HT2A Serotonin Receptor Assay (HTR2A) from Innoprot allows to assay compounds, or analyze their capability to modulate HTR2A. When a ligand binds to the HTR2A, it activates a G protein; which in turn, triggers a cellular response mediated by calcium. The binding of an agonist to HTR2A induces mobilization of intracellular calcium and also activation…
FP Prostanoid Receptor Assay (PTGFR) from Innoprot allows to assay compounds, or analyze their capability to modulate PTGFR. When a ligand binds to the PTGFR, it activates a G protein; which in turn, triggers a cellular response mediated by calcium. The binding of an agonist to PTGFR induces mobilization of intracellular calcium and also activation…
EP4 Prostanoid Receptor Assay from Innoprot measures PTGER4 receptor activation using HTRF technology. PTGER4 Receptor signaling occurs via adenylate cyclase stimulation through trimeric Gs proteins, increasing cAMP, and also downstream L-type calcium channel interaction. In this assay, we measure the receptor activation/inhibition by cAMP accumulation using HTRF technology. The high reproducibility of this assay allows…
EP2 Prostanoid Receptor Assay from Innoprot measures PTGER2 receptor activation using HTRF technology. PTGER2 Receptor signaling occurs via adenylate cyclase stimulation through trimeric Gs proteins, increasing cAMP, and also downstream L-type calcium channel interaction. In this assay, we measure the receptor activation/inhibition by cAMP accumulation using HTRF technology. The high reproducibility of this assay allows…
EP1 Prostanoid Receptor Assay (PTGER1) from Innoprot allows to assay compounds, or analyze their capability to modulate PTGER1. When a ligand binds to the PTGER1, it activates a G protein; which in turn, triggers a cellular response mediated by calcium. The binding of an agonist to PTGER1 induces mobilization of intracellular calcium and also activation…
PAC1 Receptor Assay from Innoprot measures PAC1 receptor activation using HTRF technology. PAC1 Receptor signaling occurs via adenylate cyclase stimulation through trimeric Gs proteins, increasing cAMP, and downstream L-type calcium channel interaction. In this assay, we measure the receptor activation/inhibition by cAMP accumulation using HTRF technology. The high reproducibility of this assay allows monitoring PAC1…
Delta Opioid Receptor Internalization Assay from Innoprot allows to assay compounds, or analyze their capability to modulate Delta Opioid receptor (OPRD1) activation and the following redistribution process inside the cells. When a ligand binds to the OPRD1, it activates a G protein, which internalizes in big and high intensity vesicles. This assay has been validated…
Kappa Opioid Receptor Internalization Assay from Innoprot allows to assay compounds, or analyze their capability to modulate Kappa Opioid receptor (OPRK1) activation and the following redistribution process inside the cells. When a ligand binds to the OPRK1, it activates a G protein, which internalizes in big and high intensity vesicles. This assay has been validated…
M5 Muscarinic Acetylcholine Receptor Assay (CHRM5) from Innoprot allows to assay compounds, or analyze their capability to modulate CHRM5. When a ligand binds to the CHRM5, it activates a G protein; which in turn, triggers a cellular response mediated by calcium. The binding of an agonist to CHRM5 induces mobilization of intracellular calcium and also…