Androgen Receptor Translocation Assay from Innoprot analyzes stimuli for their ability to modulate receptor nuclear translocation process. To perform this assay, we quantify the fluorescence distribution inside the cells with a High Content Imaging system. Human androgen receptor (hAR) is a ligand-dependent transcription factor responsible for the development of the male phenotype. The androgen receptor…
Thyrotropin-releasing hormone (TRH), also called thyrotropin-releasing factor (TRF) or thyroliberin, is one of the smallest hormones. It is a releasing hormone produced by the hypothalamus, that stimulates the release of TSH and prolactin. It is a tropic, tripeptidal hormone which consists of a miniature chain of just three amino acid building blocks. Secretion of thyrotropin-releasing hormone…
Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone or TSH) is a pituitary hormone that stimulates the thyroid gland. Pituitary gland produces and releases TSH into the bloodstream. It controls production of the thyroid hormones, thyroxine and triiodothyronine, by the thyroid gland by binding to receptors located on cells in the thyroid gland. Thyroxine and…
Glucocorticoid Receptor Translocation Assay from Innoprot analyzes stimuli for their ability to modulate receptor nuclear translocation process. To perform this assay, we quantify the fluorescence distribution inside the cells with a High Content Imaging system. Glucocorticoid receptors (GRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid, progesterone and androgen receptors. They…
Follicle stimulating hormone (FSH) is one of the gonadotrophic hormones, as well as luteinising hormone. It regulates the development, growth, pubertal maturation, and reproductive processes of the body. FSH and luteinizing hormone (LH) work together in the reproductive system. FSH is used commonly in infertility therapy, mainly for ovarian hyperstimulation as part of IVF. In…
The luteinizing hormone/choriogonadotropin receptor (LHCGR), also lutropin/choriogonadotropin receptor (LCGR) or luteinizing hormone receptor (LHR) is a transmembrane receptor found predominantly in the ovary and testis, but also many extragonadal organs such as the uterus and breasts. The receptor interacts with both luteinizing hormone (LH) and chorionic gonadotropins (such as hCG in humans). Its activation is…