Endothelial Cell Tube Formation Assay from Innoprot allows to analyze the effect of test-compounds to induce/inhibit new blood vessels formation. We determine the IC50 values of your compounds of interest in whole cell assays using different organ-specific endothelial cells; such as liver, renal, retinal, colonic, lung, pancreas or umbilical endothelial cells. We offer over 20…
Tumor Cell Proliferation Assay from Innoprot includes allows to analyze the effect of test-compounds to increase/decrease cell proliferation. We determine the IC50 values of your compounds of interest in whole cell assays using different techniques; such as MTT, LDH release, CellTiter or nuclei quantification. We offer over 60 different tumor cell lines for cell screening…
Tumor Cell Adhesion Assay from Innoprot allows to analyze the effect of drugs that could affect the physiological interaction between tumor and stromal cells. Besides this assay is very useful to identify adhesion molecules involving in the process of interaction with stromal cells or extracellular matrix substrates. Therefore, an in vitro cell co-culture system for…
Tumor cell migration/invasion is one of the key steps in the tumor progression. The metastatic potential of tumor cells is largely dependent on their ability to degradate and migrate through extracellular matrix. In vitro cell migration assay from Innoprot is a Boyden Chamber assay. Boyden Chambers consist of a cell culture insert nested in the…
Tumor cell migration/invasion is one of the key steps in the tumor progression. The metastatic potential of tumor cells is largely dependent on their ability to degradate and migrate through extracellular matrix. In vitro cell invasion assay from Innoprot is a Boyden Chamber assay. Boyden Chambers consist of a cell culture insert nested in the…
CCK2R (CCKBR) Human Cholecystokinin receptor assay from Innoprot provides the analysis of both signalling pathways involving GPCR activation; G protein by Calcium flux and β-arrestin recruitment using Nomad multiplex technology. The cholecystokinin B receptor (CCKBR, CCK2R) is a protein that in humans is encoded by the CCKBR gene. This gene encodes a G-protein-coupled receptor for…
Human Neurotensin receptor 1 assay (NTSR1) from Innoprot provides the analysis of both signalling pathways involving GPCR activation; G protein by Calcium flux and β-arrestin recruitment using Nomad multiplex technology. The primary transduction mechanism involves Gq/G11 family transducers, so we measure Ca2+ flux in combination with β-arrestin recruitment in this assay. Neurotensin receptor 1 belongs to…