Mostrando todos los resultados (2)

Green Fluorescent B1 Bradykinin Receptor Cell Line

Green Fluorescent B1 Bradykinin Receptor Cell Line

6.950,00

Green Fluorescent GPCR cell lines from Innoprot allows to perform GPCR internalization assays. Each vial of Green Fluorescent B1 Bradykinin Receptor Cell Line contains CHO-K1 cells stably expressing BDKRB1 tagged with tGFP.  These Cell lines proliferate in vitro maintaining fluorescent GPCR expression following the cell culture manual.

Innoprot Green Fluorescent B1 Bradykinin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate BDKRB1 activation and the following redistribution process inside the cells. When a ligand binds to the BDKRB1, it activates a G protein, which internalizes in big and high intensity vesicles. This cell line has been validated measuring Fluorescent BDKRB1 redistribution by increase of fluorescence surrounding the nuclei using image analysis algorithms. The high reproducibility of this assay allows monitoring B1 Bradykinin Receptor redistribution process in High Throughput Screening.

 

Size/Quantity: 2 vials containing 3×106 cells / vial

HiTSeeker Bradykinin receptor B1 Cell Line

HiTSeeker Bradykinin receptor B1 Cell Line

5.250,00

HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker Bradykinin receptor B1 Cell Line contains HEK293 cells stably expressing BDKRB1 with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.

Innoprot HiTSeeker BDKRB1 Cell Line allows to assay compounds, or analyze their capability to modulate BDKRB1. When a ligand binds to the BDKRB1, it activates a G protein, which in turn, triggers a cellular response mediated by a second messenger. HiTSeeker BDKRB1 cell line has been validated performing an assay with [3H] bradykinin (1 nM) and increasing concentrations of no radioactive competitor. The high reproducibility of this assay allows monitoring BDKRB1 receptor activation process in High Throughput Screening.

Size/Quantity: 2 vials containing 3×106 cells / vial