Mostrando todos los resultados (2)

Fluorescent B2 Bradykinin Receptor

Green Fluorescent B2 Bradykinin Receptor Cell Line

6.950,00

Green Fluorescent GPCR cell lines from Innoprot allows to perform GPCR internalization assays. Each vial of Green Fluorescent B2 Bradykinin Receptor Cell Line contains CHO-K1 cells stably expressing BDKRB2 tagged with tGFP.  These Cell lines proliferate in vitro maintaining fluorescent GPCR expression following the cell culture manual.

Innoprot Green Fluorescent B2 Bradykinin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate BDKRB2 activation and the following redistribution process inside the cells. When a ligand binds to the BDKRB2, it activates a G protein, which internalizes in big and high intensity vesicles. This cell line has been validated measuring Fluorescent BDKRB2 redistribution by increase of fluorescence surrounding the nuclei using image analysis algorithms. The high reproducibility of this assay allows monitoring B2 Bradykinin Receptor redistribution process in High Throughput Screening.

 

Size/Quantity: 2 vials containing 3×106 cells / vial

HiTSeeker Bradykinin receptor B2 Cell LineHiTSeeker Bradykinin receptor B2 Cell Line

HiTSeeker Bradykinin receptor B2 Cell Line

5.250,00

HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial ofHiTSeeker Bradykinin receptor B2 Cell Line contains HEK293 or U2OS cells stably expressing BDKRB2 with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.

Innoprot HiTSeeker BDKRB2 Cell Line allows to assay compounds, or analyze their capability to modulate BDKRB1. When a ligand binds to the BDKRB2, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker BDKRB2 cell line has been validated measuring calcium concentration changes in the cytosol upon activation with bradykinin. The high reproducibility of this assay allows monitoring BDKRB2 receptor activation process in High Throughput Screening.

Size/Quantity: 2 vials containing 3×106 cells / vial