HiTSeeker ETA Endothelin Receptor Cell Line
5.250,00€HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker ETA Endothelin Receptor Cell Line contains U2OS cells stably expressing ETA Receptor with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker ETA Endothelin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate ETA receptor. When a ligand binds to the ETA receptor, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker ETA Receptor cell line has been validated measuring calcium concentration changes in the cytosol upon activation with Endothelin agonist. The high reproducibility of this assay allows monitoring ETA receptor activation process in High Throughput Screening.
Size/Quantity: 2 vials containing 3×106 cells / vial