Mostrando todos los resultados (2)

Fluorescent M1 Muscarinic Acetylcholine Receptor

Green Fluorescent M1 Muscarinic Acetylcholine Receptor Cell Line

6.950,00

Green Fluorescent GPCR cell lines from Innoprot allows to perform GPCR internalization assays. Each vial of Green Fluorescent M1 Muscarinic Acetylcholine Receptor Cell Line contains CHO-K1 cells stably expressing M1 Receptor tagged with tGFP.  These Cell lines proliferate in vitro maintaining fluorescent GPCR expression following the cell culture manual.

Innoprot Green Fluorescent M1 Muscarinic Acetylcholine Receptor Cell Line allows to assay compounds, or analyze their capability to modulate M1R activation and the following redistribution process inside the cells. When a ligand binds to the M1 Receptor, it activates a G protein, which internalizes in big and high intensity vesicles. This cell line has been validated measuring Fluorescent M1 Receptor redistribution by increase of fluorescence surrounding the nuclei using image analysis algorithms. The high reproducibility of this assay allows monitoring M1 Muscarinic Acetylcholine Receptor redistribution process in High Throughput Screening.

 

Size/Quantity: 2 vials containing 3×106 cells / vial

HiTSeeker Muscarinic Acetylcholine Receptor M1 Cell LineHiTSeeker Vasopressin Receptor 1A Cell Line

HiTSeeker Muscarinic Acetylcholine Receptor M1 Cell Line

5.250,00

HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker Muscarinic Acetylcholine Receptor M1 Cell Line contains U2OS cells stably expressing CHRM1 with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.

Innoprot HiTSeeker Muscarinic Acetylcholine Receptor M1 Cell Line allows to assay compounds, or analyze their capability to modulate CHRM1. When a ligand binds to the CHRM1, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker CHRM1 cell line has been validated measuring calcium concentration changes in the cytosol upon activation with oxotremorine. The high reproducibility of this assay allows monitoring CHRM1 receptor activation process in High Throughput Screening.

Size/Quantity: 2 vials containing 3×106 cells / vial