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HiTSeeker Muscarinic Acetylcholine Receptor M3 Cell LineHiTSeeker Vasopressin Receptor 1A Cell Line

HiTSeeker Muscarinic Acetylcholine Receptor M3 Cell Line

5.250,00

HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker Muscarinic Acetylcholine Receptor M3 Cell Line contains U2OS cells stably expressing CHRM3 with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.

Innoprot HiTSeeker Muscarinic Acetylcholine Receptor M3 Cell Line allows to assay compounds, or analyze their capability to modulate CHRM3. When a ligand binds to the CHRM3, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker CHRM3 cell line has been validated measuring calcium concentration changes in the cytosol upon activation with oxotremorine. The high reproducibility of this assay allows monitoring CHRM3 receptor activation process in High Throughput Screening.

Size/Quantity: 2 vials containing 3×106 cells / vial