Mostrando el único resultado

Fluorescent Kappa Opioid Receptor

Green Fluorescent Kappa Opioid Receptor Cell Line


Green Fluorescent GPCR cell lines from Innoprot allows to perform GPCR internalization assays. Each vial of Green Fluorescent Kappa Opioid Receptor Cell Line contains U2OS cells stably expressing KOR Receptor tagged with tGFP. These Cell lines proliferate in vitro maintaining fluorescent GPCR expression following the cell culture manual.

Innoprot Green Fluorescent Kappa Opioid Receptor Cell Line allows to assay compounds, or analyze their capability to modulate KOR Receptor activation and the following redistribution process inside the cells. When a ligand binds to the KOR Receptor, it activates a G protein, which internalizes in big and high intensity vesicles. This cell line has been validated measuring Fluorescent Kappa Opioid Receptor redistribution by increase of fluorescence surrounding the nuclei using image analysis algorithms. The high reproducibility of this assay allows monitoring KOR Receptor redistribution process in High Throughput Screening.


Size/Quantity: 2 vials containing 3×106 cells / vial