Mostrando todos los resultados (2)

Fluorescent NK1 Tachykinin Receptor

Green Fluorescent NK1 Tachykinin Receptor Cell Line

6.950,00

Green Fluorescent GPCR cell lines from Innoprot allows to perform GPCR internalization assays. Each vial of Green Fluorescent NK1 Tachykinin Receptor Cell Line contains SH-SY5Y cells stably expressing NK1 Receptor tagged with tGFP. These Cell lines proliferate in vitro maintaining fluorescent GPCR expression following the cell culture manual.

Innoprot Green Fluorescent NK1 Tachykinin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate NK1 Receptor activation and the following redistribution process inside the cells. When a ligand binds to the NK1 Receptor, it activates a G protein, which internalizes in big and high intensity vesicles. This cell line has been validated measuring Fluorescent NK1 Receptor redistribution by increase of fluorescence surrounding the nuclei using image analysis algorithms. The high reproducibility of this assay allows monitoring NK1 Receptor redistribution process in High Throughput Screening.

 

Size/Quantity: 2 vials containing 3×106 cells / vial

NK1 Tachykinin Receptor Cell LineCalcium Assay

HiTSeeker NK1 Tachykinin Receptor Cell Line

5.250,00

HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker NK1 Tachykinin Receptor Cell Line contains HEK293 cells stably expressing NK1 Receptor with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.

Innoprot HiTSeeker NK1 Tachykinin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate NK1 receptor. When a ligand binds to the NK1R, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker NK1 Receptor cell line has been validated measuring calcium concentration changes in the cytosol upon activation with Substance P. The high reproducibility of this assay allows monitoring NK1 Receptor activation process in High Throughput Screening.

Size/Quantity: 2 vials containing 3×106 cells / vial