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Green Fluorescent NK3 Tachykinin Receptor Cell Line

Green Fluorescent NK3 Tachykinin Receptor Cell Line

6.950,00

Green Fluorescent GPCR cell lines from Innoprot allows to perform GPCR internalization assays. Each vial of Green Fluorescent NK3 Tachykinin Receptor Cell Line contains SH-SY5Y cells stably expressing NK3 Receptor tagged with tGFP. These Cell lines proliferate in vitro maintaining fluorescent GPCR expression following the cell culture manual.

Innoprot Green Fluorescent NK3 Tachykinin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate NK3 Receptor activation and the following redistribution process inside the cells. When a ligand binds to the NK3 Receptor, it activates a G protein, which internalizes in big and high intensity vesicles. This cell line has been validated measuring Fluorescent NK3 Receptor redistribution by increase of fluorescence surrounding the nuclei using image analysis algorithms. The high reproducibility of this assay allows monitoring NK3 Receptor redistribution process in High Throughput Screening.

 

Size/Quantity: 2 vials containing 3×106 cells / vial

NK3 Tachykinin Receptor Cell LineCalcium Assay

HiTSeeker NK3 Tachykinin Receptor Cell Line

5.250,00

HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker NK3 Tachykinin Receptor Cell Line contains U2OS cells stably expressing NK3 Receptor with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.

Innoprot HiTSeeker NK3 Tachykinin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate NK3 receptor. When a ligand binds to the NK3R, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker NK3 Receptor cell line has been validated measuring calcium concentration changes in the cytosol upon activation with Substance P. The high reproducibility of this assay allows monitoring NK3 Receptor activation process in High Throughput Screening.

Size/Quantity: 2 vials containing 3×106 cells / vial