Mostrando todos los resultados 3

GIP Receptor Cell Line

cAMPNOMAD GIP Receptor Cell Line

9.995,00

cAMPNOMAD Cells are cell lines stably co-expressing tag-free GPCRs and cAMP Nomad Biosensor to monitor G-protein modulation by cAMP release. Each vial of cAMPNOMAD GIP Receptor Cell Line contains U2OS cells stably expressing the following constructs:

  • human GIP Receptor (GIPR) with no tag
  • cAMP Nomad Biosensor (Red Fluorescence)

cAMPNOMAD GIP Receptor Cell Line allows to assay compounds analyzing the G-Protein signalling pathway by Gs involving receptor activation. When an agonist binds to GIP, the Gs protein is activated which, in turn, triggers a cellular response mediated by cAMP via adenylate cyclase stimulation. This leads to an increase of red fluorescence intensity of cAMP biosensor. So, the activity can be easily quantified on living cells in a dose-response manner by fluorescence emission in a microplate reader.

Size/Quantity: 2 vials containing 3×106 cells / vial

GLP-1 Receptor

cAMPNOMAD GLP-1 Receptor Cell Line

9.995,00

cAMPNOMAD Cells are cell lines stably co-expressing tag-free GPCRs and cAMP Nomad Biosensor to monitor G-protein modulation by cAMP release. Each vial of cAMPNOMAD GLP-1 Receptor Cell Line contains HEK293 cells stably expressing the following constructs:

  • human GLP-1 Receptor (GLP1R) with no tag
  • cAMP Nomad Biosensor (Red Fluorescence)

cAMPNOMAD GLP-1 Receptor Cell Line allows to assay compounds analyzing the G-Protein signalling pathway by Gs involving receptor activation. When an agonist binds to GLP-1, the Gs protein is activated which, in turn, triggers a cellular response mediated by cAMP via adenylate cyclase stimulation. This leads to an increase of red fluorescence intensity of cAMP biosensor. So, the activity can be easily quantified on living cells in a dose-response manner by fluorescence emission in a microplate reader.

Size/Quantity: 2 vials containing 3×106 cells / vial

GLP-2 Receptor Cell Line

cAMPNOMAD GLP-2 Receptor Cell Line

9.995,00

cAMPNOMAD Cells are cell lines stably co-expressing tag-free GPCRs and cAMP Nomad Biosensor to monitor G-protein modulation by cAMP release. Each vial of cAMPNOMAD GLP-2 Receptor Cell Line contains U2OS cells stably expressing the following constructs:

  • human GLP-2 Receptor (GLP2R) with no tag
  • cAMP Nomad Biosensor (Red Fluorescence)

cAMPNOMAD GLP-2 Receptor Cell Line allows to assay compounds analyzing the G-Protein signalling pathway by Gs involving receptor activation. When an agonist binds to GLP-2, the Gs protein is activated which, in turn, triggers a cellular response mediated by cAMP via adenylate cyclase stimulation. This leads to an increase of red fluorescence intensity of cAMP biosensor. So, the activity can be easily quantified on living cells in a dose-response manner by fluorescence emission in a microplate reader.

Size/Quantity: 2 vials containing 3×106 cells / vial