HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker Muscarinic Acetylcholine Receptor M5 Cell Line contains U2OS cells stably expressing CHRM5 with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker Muscarinic Acetylcholine Receptor M5 Cell Line allows to assay compounds, or analyze their capability to modulate CHRM5. When a ligand binds to the CHRM5, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker CHRM5 cell line has been validated measuring calcium concentration changes in the cytosol upon activation with oxotremorine. The high reproducibility of this assay allows monitoring CHRM5 receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker NK1 Tachykinin Receptor Cell Line contains HEK293 cells stably expressing NK1 Receptor with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker NK1 Tachykinin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate NK1 receptor. When a ligand binds to the NK1R, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker NK1 Receptor cell line has been validated measuring calcium concentration changes in the cytosol upon activation with Substance P. The high reproducibility of this assay allows monitoring NK1 Receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker NK2 Tachykinin Receptor Cell Line contains U2OS cells stably expressing NK2 Receptor with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker NK2 Tachykinin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate NK2 receptor. When a ligand binds to the NK2R, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker NK2 Receptor cell line has been validated measuring calcium concentration changes in the cytosol upon activation with Substance P. The high reproducibility of this assay allows monitoring NK2 Receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker NK3 Tachykinin Receptor Cell Line contains U2OS cells stably expressing NK3 Receptor with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker NK3 Tachykinin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate NK3 receptor. When a ligand binds to the NK3R, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker NK3 Receptor cell line has been validated measuring calcium concentration changes in the cytosol upon activation with Substance P. The high reproducibility of this assay allows monitoring NK3 Receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker NTSR1 Neurotensin Receptor Cell Line contains U2OS cells stably expressing NTSR1 with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker NTSR1 Neurotensin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate Neurotensin 1 receptor. When a ligand binds to the NTSR1, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker NTSR1 Receptor cell line has been validated measuring calcium concentration changes in the cytosol upon activation with Neurotensin. The high reproducibility of this assay allows monitoring NTSR1 activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker PAC1 Receptor Cell Line contains HEK293 cells stably expressing PAC1R with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker PAC1 Receptor Cell Line allows to assay compounds, or analyze their capability to modulate PAC1R. When a ligand binds to the PAC1R, it activates a G protein, which in turn, triggers a cellular response mediated by cAMP. HiTSeeker PAC1 Receptor Cell Line has been validated measuring cAMP concentration changes in the cytosol upon activation with PACAP-38. The high reproducibility of this assay allows monitoring PAC1 receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker TRH1 Thyrotropin-Releasing Hormone Receptor Cell Line contains U2OS cells stably expressing TRH1 Receptor with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker TRH1 Thyrotropin-Releasing Hormone Receptor Cell Line allows to assay compounds, or analyze their capability to modulate TRH1 receptor. When a ligand binds to the TRH1, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker TRH Receptor cell line has been validated measuring calcium concentration changes in the cytosol upon activation with TRH. The high reproducibility of this assay allows monitoring rhTRH Receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker TSH Receptor Cell Line contains HEK293 cells stably expressing human thyroid-stimulating hormone receptor with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker TSH Receptor Cell Line allows to assay compounds, or analyze their capability to modulate TSHR. When a ligand binds to the TSHR, it activates a G protein, which in turn, triggers a cellular response mediated by second messengers (cAMP). HiTSeeker TSH Receptor cell line has been validated measuring cAMP concentration changes in the cytosol upon activation with rhTSH. The high reproducibility of this assay allows monitoring TSH receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker Urotensin Receptor Cell Line contains U2OS cells stably expressing Urotensin Receptor (aka GPR14 or UTS2R) with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker Urotensin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate UT Receptor. When a ligand binds to the UT Receptor, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. HiTSeeker Urotensin Receptor cell line has been validated measuring calcium concentration changes in the cytosol upon activation with UT-II. The high reproducibility of this assay allows monitoring UT Receptor activation process in High Throughput Screening.
HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker VPAC1 Receptor Cell Line contains HEK293 cells stably expressing vasoactive intestinal peptide receptor 1 with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.
Innoprot HiTSeeker VPAC1 Receptor Cell Line allows to assay compounds, or analyze their capability to modulate VPAC1R. When a ligand binds to the VIPR1, it activates a G protein, which in turn, triggers a cellular response mediated by cAMP. HiTSeeker VPAC1 Receptor Cell Line has been validated measuring cAMP concentration changes in the cytosol upon activation with PACAP-38. The high reproducibility of this assay allows monitoring VPAC1 Receptor activation process in High Throughput Screening.
HiTSeeker NTSR1 Neurotensin Receptor Cell Line 
