SSTR3 encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. SSTR3 is present in highest levels in brain and pancreatic islets. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other GPCRs. Green Fluorescent SST3 Somatostatin Receptor Cell Line from Innoprot allows the measurement of the activity and potency of ligands; such as SST.
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