HiTSeeker FSH Receptor Cell Line

Reference: P30117

HiTSeeker FSH Receptor Cell Line

HiTSeeker are cell lines stably expressing label-free GPCRs, also known as seven-(pass)-transmembrane domain receptors. Each vial of HiTSeeker FSH Recetpor Cell Line contains HEK293 cells stably expressing human Follicle Stimulating Hormone Receptor with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual.

Innoprot HiTSeeker FSH Receptor Cell Line allows to assay compounds, or analyze their capability to modulate FSHR. When a ligand binds to the FSHR, it activates a G protein, which in turn, triggers a cellular response mediated by second messengers (cAMP). HiTSeeker FSHR cell line has been validated measuring cAMP concentration changes in the cytosol upon activation with rhFSH. The high reproducibility of this assay allows monitoring FSH receptor activation process in High Throughput Screening.

 

Size/Quantity: 2 vials containing 3×106 cells / vial

5.250,00

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Follicle stimulating hormone (FSH) is one of the gonadotrophic hormones, as well as luteinising hormone. It regulates the development, growth, pubertal maturation, and also reproductive processes of the body. FSH and luteinizing hormone (LH) work together in the reproductive system. FSH is part of the treatments for infertility therapy, mainly for ovarian hyperstimulation as part of IVF. In some cases, reversal of anovulation treatments requires FSH as well. The FSH receptor is the primary target of the approved drug urofollitropin, a recombinant form of endogenous FSH. HiTSeeker FSH Recetpor cell line from Innoprot allows the measurement of the activity and potency of ligands, such as recombinant human FSH (rhFSH).

Click HERE to know more about FSH Receptor.

 

  • Reference: P30117
  • Size/Quantity: 2 vials containing 3x106 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice