Human Epidermal Melanocytes

Reference: P10853

Human Epidermal Melanocytes

Human Epidermal Melanocytes (HEM) provided by Innoprot are isolated from human healthy skin. HEM are cryopreserved at passage one and delivered frozen. Each vial of Human Epidermal Melanocytes contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Epidermal Melanocytes which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HEM culture. You can select between Human Epidermal Melanocytes isolated from skins of different levels of pigmentation.

 

Size/Quantity: 500.000 Cells / vial

595,00

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Human Epidermal Melanocytes are neural crest-origin cells that produce melanin via melanogenesis. Melanocytes localize to several tissues including the epidermis, eye, inner ear and leptomeninges. Dysregulation of melanocyte migration, proliferation, or survival during embryonic development thus causes congenital disorders in those tissues. In the bottom layer of skin epidermis, melanocytes synthesize and transfer dark-colored melanin to surrounding keratinocytes to give skin pigmentation. Melanin also blocks UV-B light to protect the hypodermis from solar exposure-induced photodamage. Progress in culture techniques, along with an improved understanding of melanocyte biology, has led to a successful culture system to model melanomas, inner ear homeostasis, vitiligo, and mitochondrial dysfunction in Duchenne Muscular Dystrophy.

  • Reference: P10853
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice