Human Esophageal Microvascular Endothelial Cells

Reference: P10764

Human Esophageal Microvascular Endothelial Cells

Human Esophageal Microvascular Endothelial Cells (HEsMEC) provided by Innoprot are isolated from human healthy esophageal tissue. HEsMEC are cryopreserved at passage one and delivered frozen. Each vial of Human Esophageal Microvascular Endothelial Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 10 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Esophageal Microvascular Endothelial Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HEsMEC culture.

 

Size/Quantity: 500.000 Cells / vial

835,00

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Endothelial cells lining the microvasculature play a critical “gatekeeper” role in the inflammatory process through their ability to recruit circulating immune cells into tissues and foci of inflammation. Human Esophageal Microvascular Endothelial Cells (HEsMEC) exhibit a strong inflammatory immune response to LPS, cytokines, and pH exposure, thus playing a critical regulatory role in esophageal inflammation. When exposed to acidic pH, HEsMEC express certain proteins, such as VCAM-1, but not others, such as ICAM-1. This expression pattern could play a role in the cellular response triggered by gastroesophageal reflux disease. HEsMEC cultures have enabled scientists to observe leukocyte binding, upregulation of cell adhesion molecules, and other cellular responses to LPS, cytokines and pH exposure. HEsMEC are intrinsically different from lower gastrointestinal endothelial cells.

  • Reference: P10764
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice