Human Leydig Cells

Reference: P10795

Human Leydig Cells

Human Leydig Cells (HLC) provided by Innoprot are isolated from human healthy testis. HLC are cryopreserved at passage one and delivered frozen. Each vial of Human Leydig Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 5 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Leydig Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HLC culture.

 

Size/Quantity: 500.000 Cells / vial

840,00

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Human Leydig Cells (LC) are located in the interstitium of the testis near the seminiferous tubules. One of the main functions of LC is to produce testosterone after stimulation by pituitary luteinizing hormone. LC, through synthesis of testosterone, play a key role in mammalian sex determination by inducing differentiation of the Wolffian ducts into male reproductive organs. Additionally, LC produce insulin-like growth factor 3 which is necessary for scrotal descent of the testis. Recent studies indicates that molecules such as cyclic nucleotide phosphodiesterases can modulate testosterone production in LC; suggesting that pharmacological targeting may manipulate testosterone synthesis. Cultured Human LC are a useful in vitro model to better understand testicular development and also to develop treatments for male reproductive disorders. They are also useful tools to stablish in vitro disease models for High Throughput and High Content Screening.

  • Reference: P10795
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice