Human Mammary Fibroblasts

Reference: P10893

Human Mammary Fibroblasts

Human Mammary Fibroblasts (HMF) provided by Innoprot are isolated from human healthy breast. HMF are cryopreserved at passage one and delivered frozen. Each vial of Human Mammary Fibroblasts contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Mammary Fibroblasts which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HMF culture.

 

Size/Quantity: 500.000 Cells / vial

720,00

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Fibroblasts are mesenchymal cells which came from the embryonic mesoderm. Human Mammary fibroblasts (HMF) synthesize components of the stromal extracellular matrix of the mammary gland. More importantly, such stromal extracellular matrix regulates the proliferation and differentiation of mammary epithelial cells by influencing their gene expression. In addition, HMF play a role in recruiting macrophages for immune surveillance which, in concert with extracellular matrix turnover and angiogenesis, is related with a supportive mammary microenvironment for tumor cell progression. These results suggest that MF play a stimulatory functional role in breast cancer development and invasion. Human Mammary Fibroblasts provide an invaluable tool for understanding physiological and pathophysiological relevance in mammary function and disease.

  • Reference: P10893
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice