Human Sertoli Cells

Reference: P10796

Human Sertoli Cells

Human Sertoli Cells (HSerC) provided by Innoprot are isolated from human healthy testis. HSerC are cryopreserved at passage one and delivered frozen. Each vial of Human Sertoli Cells contains more than 500.000 viable cells. They are guaranteed to further expand for 15 population doublings following the instructions provided in the technical sheet.

Innoprot also offers optimized medium and reagents for the growth of Human Sertoli Cells which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro HSerC culture.

 

Size/Quantity: 500.000 Cells / vial

840,00

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Human Sertoli Cells (SerC) are essential for testicular development, spermatogenesis, and formation of the blood-testis barrier. SerC limit the passage of substances such as hormones and nutrients to the adluminal compartment of the seminiferous tubules. In addition to forming the blood-testis barrier, SerC also provide the main structural support for the seminiferous tubules. They protect the germ cells from the immune system. Aberrant SerC proliferation can contribute to the development of male reproductive disorders; such as testicular germ-cell cancer, cryptorchidism, hypospadias, and low sperm count. SerC proliferation is in part dependant by follicle-stimulating hormone (FSH) and thyroid hormone (TH), where FSH drives proliferation and TH promotes a more quiescent state. Cultured Human SerC are a useful in vitro model to better understand testicular dysgenesis syndrome and to develop treatments for male reproductive disorders.

  • Reference: P10796
  • Size/Quantity: 5x105 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice