Immortalized Human Dermal Microvascular Endothelial Cells

Reference: P10861-IM

Immortalized Human Dermal Microvascular Endothelial Cells

Immortalized Human Dermal Microvascular Endothelial Cells (IM-HDMEC) provided by Innoprot have been developed by immortalizing primary human dermal endothelial cells with SV40 Large T antigen.

Immortalized cells were controlled passaging side by side with the primary cells. Primary cells go into senescence after the 3rd passage while the SV40‐tranduced cells go beyond 30 passages.

Each vial of IM-HDMEC contains more than 1 million viable cells. Innoprot also offers optimized medium and reagents for the growth of IM-HDMEC which are quality tested together and guaranteed to give maximum performance as a global solution for in vitro IM-HDMEC culture.

 

Size/Quantity: 1 million cells / vial

1.950,00

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Blood vessels of the skin contains both, cellular and non-cellular elements. The predominant cell type in all skin blood vessels is endothelial cells. Endothelial cells form the interface between intravascular and extravascular compartments. They serve as a selective barrier for the diffusion of cells and macromolecules between these two compartments. While endothelial cells lining blood vessels of the skin share features of endothelial cells elsewhere in the body, they also exhibit several skin specific characteristics. Human Dermal Microvascular Endothelial Cells provide an invaluable tool for understanding DMEC physiological and pathophysiological relevance in dermal function. Immortalized Human Dermal Microvascular Endothelial Cells also allow to stablish in vitro models for HIgh Throughput and High Content Screening.

 

  • Reference: P10861-IM
  • Size/Quantity: 1x106 cells / vial
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice