The neurotensin receptors are transmembrane receptors that bind the neurotransmitter neurotensin. Neurotensin (NT) is a brain and gastrointestinal peptide. It fulfills a dual function of neurotransmitter or neuromodulator in the nervous system and of local hormone in the periphery. NTSR1 and NTSR2 genes contain seven transmembrane helices and are GPCRs. NTSR1 mediates multiple biological through modulation by neurotensin; such as low blood pressure, high blood sugar, low body temperature, antinociception, and regulation of intestinal motility and secretion. MPXNOMAD NTS1 Neurotensin Receptor Cell Line from Innoprot allows the measurement of the activity and potency of ligands; such as Neurotensin.
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