ACE2 Cell Line

Reference: P30902

ACE2 Cell Line

The ACE2 cell line from Innoprot has been developed stably transfecting HEK293 cell line with a angiotensin I converting enzyme 2 (ACE2) protein expression plasmid. ACE2 HEK293 cell line provides consistent levels of expression of human ACE2 protein in cells surface. Each vial of cells contains more than 3 million viable cells stably expressing ACE2 with hygromycin resistance gene.

ACE2 HEK293 Cell line is ready to use in cell-based assay applications, such as Screening for ACE2 inhibitors. This stably transfected clonal cell line provides consistent levels of expression, which helps simplify the interpretation of results. ACE2 HEK293 Cell line also allow to stablish in vitro models for High Throughput and High Content Screening.


ACE2 cell line from Innoprot stable expresses ACE2. Angiotensin I converting enzyme 2, a.k.a. ACE2, is a carboxypeptidase that potently degrades angiotensin II to angiotensin 1–7. It also plays a key role in the renin-angiotensin system (RAS). The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2 (COVID-19 virus). ACE2 cell line allows the study of SARS-CoV-2 spike/ACE2 interaction in cell-based assays.

More information about ACE2.

  • Reference: P30902
  • Size/Quantity: 3x106 cells / vial
  • Resistance Gene: Hygromycin
  • Product Use: For research use only
  • Shipping Conditions: Dry Ice